Robert Flick

A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair

Mohan Babu, Natalia Beloglazova, Robert Flick et al. · Molecular Microbiology · 2010 · 263 citations · Full text

Engineering, Genetics, Immunology +16

Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutières Syndrome and HIV-1 Restriction

Natalia Beloglazova, Robert Flick, Anatoli Tchigvintsev et al. · Journal of Biological Chemistry · 2013 · 215 citations · Full text

Viral Replication, Immunology, Molecular Biology +18

Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson’s disease factors Pink1 and Parkin

Alexander J. Whitworth, Jeffrey R. Lee, Venus M.-W. Ho et al. · Disease Models & Mechanisms · 2008 · 185 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Genetics +21

Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases

Mahbod Hajighasemi, B. Nocek, Anatoli Tchigvintsev et al. · Biomacromolecules · 2016 · 184 citations

Engineering, Biopolymer Production, Polysaccharide +18

SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

Constanze Schneider, Thomas Oellerich, Hanna‐Mari Baldauf et al. · Nature Medicine · 2016 · 166 citations

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +8