Kohei Kawata

RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists

Hiroki Kakuta, Nobumasa Yakushiji, Ryosuke Shinozaki et al. · ACS Medicinal Chemistry Letters · 2012 · 45 citations · Full text

Pharmacotherapy, Glucose Tolerance, Insulin Signaling +17

Mechanism of Retinoid X Receptor Partial Agonistic Action of 1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1<i>H</i>-benzotriazole-5-carboxylic Acid and Structural Development To Increase Potency

Fuminori Ohsawa, Shoya Yamada, Nobumasa Yakushiji et al. · Journal of Medicinal Chemistry · 2013 · 43 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Molecular Pharmacology +16

RXR Partial Agonist Produced by Side Chain Repositioning of Alkoxy RXR Full Agonist Retains Antitype 2 Diabetes Activity without the Adverse Effects

Kohei Kawata, Ken-ichi Morishita, Mariko Nakayama et al. · Journal of Medicinal Chemistry · 2014 · 21 citations

Pharmacotherapy, Pharmaceutical Chemistry, Molecular Pharmacology +16

Discovery of a Potent Retinoid X Receptor Antagonist Structurally Closely Related to RXR Agonist NEt-3IB

Mariko Nakayama, Shoya Yamada, Fuminori Ohsawa et al. · ACS Medicinal Chemistry Letters · 2011 · 12 citations · Full text

Rxr Antagonist Pa452, Pharmacotherapy, Chemical Biology +16