David H. Lum

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

Conan G. Kinsey, Soledad A. Camolotto, Amélie Boespflug et al. · Nature Medicine · 2019 · 648 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Plasma exosome microRNAs are indicative of breast cancer

Bethany N. Hannafon, Yvonne D. Trigoso, Cameron L. Calloway et al. · Breast Cancer Research · 2016 · 617 citations · Full text

Medicine, Molecular Biology, Oncology +17

Direct protein–protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in <i>C. elegans</i>

David H. Lum, Patricia E. Kuwabara, David Zarkower et al. · Genes & Development · 2000 · 399 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Katrin P. Guillen, Maihi Fujita, Andrew Butterfield et al. · Nature Cancer · 2022 · 397 citations · Full text

Medicine, Oncology, Pharmacology +17

A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis

Qiyu Feng, Chengliang Zhang, David H. Lum et al. · Nature Communications · 2017 · 253 citations · Full text

Medicine, Cancer Biology, Oncology +16