Josephine Nemegeer

ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation

Richard de Reuver, Simon Verdonck, Evelien Dierick et al. · Nature · 2022 · 236 citations · Full text

Life Sciences, Immunology, Molecular Biology +5

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

Michaël Devos, Giel Tanghe, Barbara Gilbert et al. · The Journal of Experimental Medicine · 2020 · 122 citations · Full text

Life Sciences, Dermatology, Molecular Biology +17

<i>GTF3A</i> mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand <i>RNA5SP141</i>

Leslie Naesens, Santoshi Muppala, Dhiraj Acharya et al. · Science Immunology · 2022 · 35 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Mutations in RNU7-1 Weaken Secondary RNA Structure, Induce MCP-1 and CXCL10 in CSF, and Result in Aicardi-Goutières Syndrome with Severe End-Organ Involvement

Leslie Naesens, Josephine Nemegeer, Filip Roelens et al. · Journal of Clinical Immunology · 2022 · 22 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

Michaël Devos, Giel Tanghe, Barbara Gilbert et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 16 citations · Full text

Life Sciences, Dermatology, Molecular Biology +17