The viral protein corona directs viral pathogenesis and amyloid aggregation

Kariem Ezzat, Maria Pernemalm, Sandra Pålsson, +23

Nature Communications

Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing

Sandra Wimberger, Nina Akrap, Mike Firth, +25

Nature Communications

Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing

Martin Peterka, Nina Akrap, Songyuan Li, +11

Nature Communications

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

Burcu Bestas, Pedro M. D. Moreno, K. Emelie M. Blomberg, +16

Journal of Clinical Investigation

Btk MrnaKnockout MouseNovel TherapyNatural SciencesTyrosine Kinase +13

Optimizing anti-gene oligonucleotide ‘Zorro-LNA’ for improved strand invasion into duplex DNA

Eman M. Zaghloul, Andreas S. Madsen, Pedro M. D. Moreno, +7

Nucleic Acids Research

Bioorganic ChemistryChemical CompositionGeneticsDna AnalysisMolecular Biology +18

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

Pedro M. D. Moreno, Sylvain Geny, Y. Vladimir Pabon, +11

Nucleic Acids Research

EngineeringBis-locked Nucleic AcidLna ContentSupercoiled Duplex DnaDna Analysis +18

Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes

Mihaela Zabulica, Raghuraman C. Srinivasan, Pınar Akçakaya, +21

Molecular Therapy

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency

Helena Sork, Joel Z. Nordin, Janne J. Turunen, +14

Molecular Therapy — Nucleic Acids

EngineeringMolecular BiologyGene DeliveryTransfection EfficiencyGene Transfer +14

The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation

Kariem Ezzat, Maria Pernemalm, Sandra Pålsson, +23

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

Burcu Bestas, Sandra Wimberger, Dmitrii Degtev, +24

Nature Communications

EngineeringGeneticsMolecular BiologyMolecular GeneticsGenomics +20