Caroline A. Blakemore

Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle

Richard L. Mackman, Victoria A. Steadman, David K. Dean et al. · Journal of Medicinal Chemistry · 2018 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss

Michelle R. Garnsey, Aaron Smith, Jana Polívková et al. · Journal of Medicinal Chemistry · 2023 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Scalable, Telescoped Hydrogenolysis–Enzymatic Decarboxylation Process for the Asymmetric Synthesis of (<i>R</i>)-α-Heteroaryl Propionic Acids

Caroline A. Blakemore, Scott P. France, Lacey Samp et al. · Organic Process Research & Development · 2020 · 16 citations

Natural Sciences, Biochemistry, Chemistry +10