MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition

Marta Kovatcheva, David D. Liu, Mark A. Dickson, +9

Oncotarget

ATRX is a regulator of therapy induced senescence in human cells

Marta Kovatcheva, Will Liao, Mary E. Klein, +7

Nature Communications

Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells

Vanessa López-Polo, Máté Maus, Emmanouil Zacharioudakis, +6

Nature Communications

Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair

Marta Kovatcheva, Elena Melendez, Dafni Chondronasiou, +13

Nature Metabolism

Deciphering the roadmap of in vivo reprogramming toward pluripotency

Dafni Chondronasiou, Jaime Martínez de Villarreal, Elena Melendez, +7

Stem Cell Reports

Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma

Caroline E. Gleason, Mark A. Dickson, Mary E. Klein, +33

Clinical Cancer Research

Cyclophilin D plays a critical role in the survival of senescent cells

Margherita Protasoni, Vanessa López-Polo, Camille Stephan‐Otto Attolini, +7

The EMBO Journal

Higher circulating vitamin <scp>B12</scp> is associated with lower levels of inflammatory markers in individuals at high cardiovascular risk and in naturally aged mice

Inés Domínguez‐López, Marta Kovatcheva, Rosa Casas, +6

Journal of the Science of Food and Agriculture

H4K20me3-Mediated Repression of Inflammatory Genes Is a Characteristic and Targetable Vulnerability of Persister Cancer Cells

Valentina Ramponi, Laia Richart, Marta Kovatcheva, +6

Cancer Research

HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells

Clara Alcon, Marta Kovatcheva, Paula Morales-Sánchez, +8

Cell Death and Differentiation