Emmanouil Zacharioudakis

Apoptotic stress causes mtDNA release during senescence and drives the SASP

Stella Victorelli, Hanna Salmonowicz, James Chapman et al. · Nature · 2023 · 600 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A

Agostinho G. Rocha, Antonietta Franco, Andrzej M. Krezel et al. · Science · 2018 · 252 citations

Life Sciences, Neurobiology, Neuroscience +17

Modulating mitofusins to control mitochondrial function and signaling

Emmanouil Zacharioudakis, Bogos Agianian, Vasantha Kumar MV et al. · Nature Communications · 2022 · 110 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Inhibitors of BRAF dimers using an allosteric site

Xiomaris M. Cotto-Rios, Bogos Agianian, Nadege Gitego et al. · Nature Communications · 2020 · 84 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis et al. · Cancer Discovery · 2023 · 75 citations · Full text

Medicine, Oncology, Pharmacology +17