Michael L.J. Ashford

Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

Kenneth R. Watterson, Dawn Bestow, Jennifer Gallagher et al. · Neurosignals · 2012 · 3.4K citations · Full text

Life Sciences, Endocrinology, Physiology +17

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.8K citations

Life Sciences, Biochemistry, Cell Biology +12

Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels

David Spanswick, Mark A. Smith, V E Groppi et al. · Nature · 1997 · 628 citations

Life Sciences, Neurobiology, Neuroscience +14

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Marc Claret, Mark A. Smith, Rachel L. Batterham et al. · Journal of Clinical Investigation · 2007 · 503 citations · Full text

Life Sciences, Neuroscience, Physiology +17

THE SULPHONYLUREA RECEPTOR MAY BE AN ATP-SENSITIVE POTASSIUM CHANNEL

NicholasC Sturgess, DanielL. Cook, Michael L.J. Ashford et al. · The Lancet · 1985 · 502 citations

Life Sciences, Pharmacology, Physiology +10