Concepedia

Helen I. Woodroof

HI

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Publications

7

Citations

1.6K

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7

Active since

2011

Affiliations

University of Dundee(Current)

MRC Protein Phosphorylation and Ubiquitylation Unit

University of Sheffield

Helen I. Woodroof is an author at University of Dundee specializing in molecular biology, cell signaling, and cell biology.

Top concepts

Publications per year

2011–2017

7

Publications

7

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang et al. · Open Biology · 2012 · 922 citations · Full text

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Phosphoproteomic screening identifies Rab <scp>GTP</scp> ases as novel downstream targets of <scp>PINK</scp> 1

Yu‐Chiang Lai, Chandana Kondapalli, Ronny Lehneck et al. · The EMBO Journal · 2015 · 184 citations · Full text

Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity

Agne Kazlauskaite, Van Kelly, Clare Johnson et al. · Open Biology · 2014 · 141 citations · Full text

Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations

Helen I. Woodroof, Joe H. Pogson, Mike Begley et al. · Open Biology · 2011 · 106 citations · Full text

Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations

Atul Kumar, J. Tamjar, Andrew D. Waddell et al. · eLife · 2017 · 101 citations · Full text

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