Thomas N. Nanninga

The convergent synthesis of CI-981, an optically active, highly potent, tissue selective inhibitor of HMG-CoA reductase

Kelvin L. Baumann, Donald E. Butler, Carl F. Deering et al. · Tetrahedron Letters · 1992 · 121 citations

Aldo-keto Reductase, Novel Therapy, Biochemistry +8

The synthesis of (4R-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, a key intermediate for the preparation of CI-981, a highly potent, tissue selective inhibitor of HMG-CoA reductase

Philip L. Brower, Donald E. Butler, Carl F. Deering et al. · Tetrahedron Letters · 1992 · 99 citations

Medicinal Chemistry, Key Intermediate, Aldo-keto Reductase +10

Development of a Scalable Process for CI-1034, an Endothelin Antagonist

Thomas E. Jacks, Daniel T. Belmont, Christopher A. Briggs et al. · Organic Process Research & Development · 2004 · 55 citations

Organic Chemistry, Pharmacotherapy, Chemistry +18

Palladium-mediated cycloaddition approach to loganin aglucon

Barry M. Trost, Thomas N. Nanninga · Journal of the American Chemical Society · 1985 · 51 citations

Bioorganic Chemistry, Engineering, Altmetric Attention Score +19

Chemoselectivity in palladium-mediated cycloadditions of substituted trimethylenemethanes

Barry M. Trost, Thomas N. Nanninga, Tsuyoshi Satoh · Journal of the American Chemical Society · 1985 · 50 citations

Molecular Sciences, Palladium-mediated Cycloadditions, Heterocyclic +10