Concepedia

Tobias Schmelzle

TS

32

Publications

5.4K

Citations

29

H-Index

1999

Active since

Affiliations

Novartis (Switzerland)(Current)

Novartis Institutes for BioMedical Research

University of Basel

Novartis (United States)

Friedrich Miescher Institute

Tobias Schmelzle is an author at Novartis (Switzerland) specializing in medicine, cell biology, and cell signaling.

Top concepts

MedicineCell BiologyCell SignalingNatural SciencesMolecular BiologySignal TransductionTumor BiologySystems BiologyCellular BiochemistryGenetics

Publications per year

1999–2024

32

Publications

32

Engineering tumors with 3D scaffolds

Claudia Fischbach, Ruth Chen, Takuya Matsumoto et al. · Nature Methods · 2007 · 814 citations

Tissue Engineering, Scaffolds, Engineering +7

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 687 citations · Full text

Bioinformatics, Tumor Biology, Radiation Oncology +13

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Konstantinos J. Mavrakis, E. Robert McDonald, Michael R. Schlabach et al. · Science · 2016 · 538 citations

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

Claudia Stein, Anaïs F. Bardet, Guglielmo Roma et al. · PLoS Genetics · 2015 · 413 citations · Full text

Hippo Pathway Components, Molecular Regulation, Genetics +22

CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions

Diana M. Muñoz, Pamela J. Cassiani, Li Li et al. · Cancer Discovery · 2016 · 373 citations

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