Laxminarayan G. Hegde

Author

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

Hegde, Laxminarayan G., L HEGDE, L. G. Hegde, L.G HEGDE, L.G. Hegde, Laxminarayan G Hegde, Laxminarayan G. Hegde

Publications

693

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)Lundbeck (United States)United States Military Academy Central Drug Research Institute Target (United States)

About

Laxminarayan G. Hegde is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, pharmacology, and pharmacotherapy.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	240
2	Natural Sciences	2	2	34
3	Biochemistry	2	2	34
4	Social Sciences	1	1	43
5	Chemical Biology	1	1	19

Laxminarayan G. Hegde

Publications

650

Citations

H-Index

Page 1

	Year	Citations
Efficacy of the MCHR1 Antagonist N-[3-(1-{[4-(3,4-Difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in Mouse Models of Anxiety and Depression following Acute and Chronic Administration Is Independent of Hippocampal Neurogenesis Denis J. David, Kristen C. Klemenhagen, Kerri A Holick, Journal of Pharmacology and Experimental Therapeutics	2007	127
Concomitant Angiotensin AT1 Receptor Antagonism and Neprilysin Inhibition Produces Omapatrilat-like Antihypertensive Effects Without Promoting Tracheal Plasma Extravasation in the Rat Laxminarayan G. Hegde, Cecile Yu, Travis Renner, Journal of Cardiovascular Pharmacology HypertensionCardiovascular PharmacologyPharmacotherapyBlood PressureAtherosclerosis	2011	64
The Novel Neuropeptide Y Y5 Receptor Antagonist Lu AA33810 [N-[[trans-4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] Exerts Anxiolytic- and Antidepressant-Like Effects in Rat Models of Stress Sensitivity Mary W. Walker, Toni D. Wolinsky, Vrej Jubian, Journal of Pharmacology and Experimental Therapeutics	2008	60
Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity Yanxia Guo, Kenzie D. MacIsaac, Yi Chen, Cell Reports	2016	58
The effects of stressful stimuli and hypothalamic–pituitary–adrenal axis activation are reversed by the melanin-concentrating hormone 1 receptor antagonist SNAP 94847 in rodents Daniel G. Smith, Laxminarayan G. Hegde, Toni D. Wolinsky, Behavioural Brain Research Hypothalamic CircuitsMelanin-concentrating Hormone 1Stress HormoneEndocrine MechanismStress	2008	43
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors Mitchell H. Keylor, Anmol Gulati, Solomon D. Kattar, Journal of Medicinal Chemistry	2021	40
Endothelin-receptor antagonists: current and future perspectives Abhijit Ray, Laxminarayan G. Hegde, Anita Chugh, Drug Discovery Today Molecular PhysiologyMedicinePhysiologyEndothelial DysfunctionVascular Biology	2000	33
ROLE OF ENDOTHELIAL-DERIVED REACTIVE OXYGEN SPECIES AND NITRIC OXIDE IN NOREPINEPHRINE-INDUCED RAT AORTIC RING CONTRACTIONS Pratima Srivastava, Laxminarayan G. Hegde, G. K. Patnaik, Pharmacological Research InflammationCardiovascular DiseaseNitrosative StressVascular AdaptationPhysiology	1998	30
Alterations in the Vasoreactivity of Hypertensive Rat Aortic Rings: Role of Nitric Oxide and Superoxide Radicals Laxminarayan G. Hegde, Pallavi Srivastava, Ranjana Kumari, Clinical and Experimental Hypertension HypertensionNitric OxideRenal InflammationSpontaneous ReleaseCardiovascular Function	1998	25
Discovery of <i>N</i>-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases Hongjun Zhang, Blair T. Lapointe, Neville J. Anthony, ACS Medicinal Chemistry Letters	2020	24

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