Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome

Xin Wang, Yingjun Zhao, Xiaofei Zhang, +19

Nature Medicine

Synaptic PlasticityNeurophysiologySocial SciencesGlutamate ReceptorNeurology +7

TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation

Siew Wee Chan, Chun Jye Lim, Li Shen Loo, +3

Journal of Biological Chemistry

Oncogenic AgentNatural SciencesGeneticsMolecular BiologyOncogenic Transformation +3

An oncogenic role of Agrin in regulating focal adhesion integrity in hepatocellular carcinoma

Sayan Chakraborty, Manikandan Lakshmanan, Hannah L. F. Swa, +9

Nature Communications

A role for sorting nexin 27 in AMPA receptor trafficking

Li Shen Loo, Ning Tang, Muthafar Al‐Haddawi, +2

Nature Communications

NeurotransmitterMolecular BiologyNeurotransmissionCellular PhysiologyMolecular Sorting +16

Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of <i>N</i>-Methyl-<scp>d</scp>-Aspartate Receptor 2C (NR2C)

Lei Cai, Li Shen Loo, Vadim Atlashkin, +2

Molecular and Cellular Biology

Signal TransductionMolecular PhysiologyDevelopmental BiologyElevated LevelsSnx27 Gene +9

Imaging synaptic inhibition in transgenic mice expressing the chloride indicator, Clomeleon

Ken Berglund, Wolfram Schleich, Patrik Krieger, +6

Brain Cell Biology

NeurotransmitterMolecular BiologyNeurotransmissionTransgenic MiceCellular Neurobiology +14

p125A exists as part of the mammalian Sec13/Sec31 COPII subcomplex to facilitate ER-Golgi transport

Yan Shan Ong, Bor Luen Tang, Li Shen Loo, +1

The Journal of Cell Biology

Protein SecretionCoat Protein IiMolecular BiologyCytoskeletonCellular Physiology +17

Safety and efficacy of evobrutinib in relapsing multiple sclerosis (evolutionRMS1 and evolutionRMS2): two multicentre, randomised, double-blind, active-controlled, phase 3 trials

Xavier Montalbán, Patrick Vermersch, Douglas L. Arnold, +17

The Lancet Neurology

Neurological ProgressClinical TrialsNeurologyMultiple SclerosisMedicine +1

Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth

Audrey Chan, Thomas Clairfeuille, Euphemie Landao‐Bassonga, +9

Molecular Biology of the Cell

SclerostinPthr SignalingBone RepairParathyroid Hormone 1Osteoporosis +17

Lasmiditan for the acute treatment of migraine: Subgroup analyses by prior response to triptans

Kerry Knievel, Andrew Buchanan, Louise Lombard, +6

Cephalalgia