UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

Petra Schwertman, Anna Lagarou, Dick H. W. Dekkers, +8

Nature Genetics

Transcriptional RegulationGenome InstabilitySignal TransductionCell RegulationMolecular Regulation +9

Experimental Evidence for Enhanced Receptor Binding by Rapidly Spreading SARS-CoV-2 Variants

Charlie Laffeber, Kelly de Koning, Roland Kanaar, +1

Journal of Molecular Biology

The miniature CRISPR-Cas12m effector binds DNA to block transcription

Wen Y. Wu, Prarthana Mohanraju, Chunyu Liao, +16

Molecular Cell

Transcriptional RegulationNatural SciencesMolecular BiologyDna ReplicationGenome Engineering +7

The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination

Nathalie van den Tempel, Charlie Laffeber, Hanny Odijk, +4

Oncotarget

Rad51 Focus FormationDna DamageRadiation EffectRadiation ExposureMolecular Biology +17

Guide-free Cas9 from pathogenic <i>Campylobacter jejuni</i> bacteria causes severe damage to DNA

Chinmoy Saha, Prarthana Mohanraju, Andrew Stubbs, +19

Science Advances

The selection process of licensing a DNA mismatch for repair

Rafael Fernández-Leiro, D. Bhairosing-Kok, Vladislav Kunetsky, +8

Nature Structural & Molecular Biology

Genome InstabilityNatural SciencesGeneticsDna AnalysisDna Replication +5

The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair

Yannicka Mardenborough, Kateryna Nitsenko, Charlie Laffeber, +9

Nucleic Acids Research

ChromatinGenome InstabilityUnstructured Linker ArmsGenome SurgeryStrand Incision +13

Experimental evidence for enhanced receptor binding by rapidly spreading SARS-CoV-2 variants

Charlie Laffeber, Kelly de Koning, Roland Kanaar, +1

Viral PathogenesisImmunologyImmunodominanceMolecular BiologyViral Structural Protein +14

An immunoaffinity purification method for the proteomic analysis of ubiquitinated protein complexes

Petra Schwertman, Karel Bezstarosti, Charlie Laffeber, +3

Analytical Biochemistry

ImmunologyProteasomeMolecular BiologyCell DeathProtein Ubiquitination +19

Biallelic <i>PAX5</i> mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder

Fabian Kaiser, Sarah Gruenbacher, Maria Roa Oyaga, +24

The Journal of Experimental Medicine

Brain DevelopmentGeneticsPathologyPrimary Antibody DeficienciesSocial Sciences +19