Redox Regulation of the DNA Binding Activity in Transcription Factor PEBP2

Yoshiko Akamatsu, Tetsuya Ohno, Kiichi Hirota, +3

Journal of Biological Chemistry

Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences

Yoshiko Akamatsu, Marjorie A. Oettinger

Molecular and Cellular Biology

ChromatinRag1-rag2 ComplexDna SequencingJ CleavageNatural Sciences +13

Essential residues in V(D)J recombination signals.

Yoshiko Akamatsu, Naoya Tsurushita, Fumikiyo Nagawa, +4

The Journal of Immunology

Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice

Yoshiko Akamatsu, R. J. Monroe, Darryll D. Dudley, +6

Proceedings of the National Academy of Sciences

Bypassing immunization: optimized design of "designer T cells" against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA.

Kathleen F. Nolan, Yoshiko Akamatsu, J. C. Murphy, +3

PubMed

T-regulatory CellImmunologyAntigen ProcessingImmune Cell TherapyT Cells +17

Functional Dissection of the α and β Subunits of Transcription Factor PEBP2 and the Redox Susceptibility of Its DNA Binding Activity

Hiroshi Kagoshima, Yoshiko Akamatsu, Yoshiaki Ito, +1

Journal of Biological Chemistry

Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing

C.M. Forsyth, Veronica Juan, Yoshiko Akamatsu, +8

mAbs

BioinformaticsMammalian Cell DisplayImmunocytochemical TechniqueEngineeringPoint Mutations +13

An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy

Sarah Chan, Nicole A. Belmar, Sun K. Ho, +38

Nature Cancer

Whole IgG surface display on mammalian cells: Application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies

Yoshiko Akamatsu, Kanokwan Pakabunto, Zhenghai Xu, +2

Journal of Immunological Methods

Immunocytochemical TechniqueAutoimmune DiseaseLaboratory ImmunologyMedicineImmunology +6

A Bispecific Molecule Targeting CD40 and Tumor Antigen Mesothelin Enhances Tumor-Specific Immunity

Shiming Ye, Diane Cohen, Nicole A. Belmar, +16

Cancer Immunology Research