Leigh Anne F. Ihnken

Chiral synthesis of LSD1 inhibitor GSK2879552 enabled by directed evolution of an imine reductase

Markus Schöber, Chris MacDermaid, Anne A. Ollis et al. · Nature Catalysis · 2019 · 218 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox

Gheorghe‐Doru Roiban, Marcelo Kern, Zhi Liu et al. · ChemCatChem · 2017 · 97 citations

Engineering, Biochemistry, Chemistry +15

<i>In Vitro</i> Reconstitution and Substrate Specificity of a Lantibiotic Protease

Leigh Anne F. Ihnken, Champak Chatterjee, Wilfred A. van der Donk · Biochemistry · 2008 · 71 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15

Distributive and Directional Behavior of Lantibiotic Synthetases Revealed by High-Resolution Tandem Mass Spectrometry

M. Violet Lee, Leigh Anne F. Ihnken, Young Ok You et al. · Journal of the American Chemical Society · 2009 · 49 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Lacticin 481 Synthetase as a General Serine/Threonine Kinase

Young Ok You, Matthew R. Levengood, Leigh Anne F. Ihnken et al. · ACS Chemical Biology · 2009 · 39 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17