Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution

J J de Jong, Anthony de Ronde, Wilco Keulen, +2

Journal of Virology

Viral ReplicationImmunologyMolecular BiologyViral Structural ProteinVirus Phenotype +15

Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

Nicole Back, Monique Nijhuis, Wilco Keulen, +5

The EMBO Journal

Primary ImmunodeficiencyReverse Transcriptase EnzymeViral ReplicationMedicineViral Polymerase Mechanism +9

Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity

J J de Jong, Jaap Goudsmit, Wilco Keulen, +4

Journal of Virology

Viral ReplicationSyncytium FormationImmunologyMolecular BiologyHiv-1 Isolates +14

Characterization, sequence determination, and immunogenicity of a 64-kilodalton protein of Mycobacterium bovis BCG expressed in escherichia coli K-12

J E Thole, Wilco Keulen, Jacqueline De Bruyn, +5

Infection and Immunity

Strong ReactivitySequence DeterminationHumoral ResponseBacteriologyImmunology +18

An N-Glycan within the Human Immunodeficiency Virus Type 1 gp120 V3 Loop Affects Virus Neutralization

Nicole Back, Lia Smit, Jean-Jacques De Jong, +4

Virology

Molecular VirologyHuman RetrovirusGlycobiologyImmunologyAntiviral Response +5

Evolution of the V3 envelope domain in proviral sequences and isolates of human immunodeficiency virus type 1 during transition of the viral biological phenotype

Carla Kuiken, J J de Jong, Elly Baan, +3

Journal of Virology

Viral ReplicationImmunologyPathologyViral Biological PhenotypeProviral Sequences +15

Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes

Anthony de Ronde, Bep Klaver, Wilco Keulen, +2

Virology

Viral ReplicationHuman RetrovirusImmunologyAntiviral ResponseVirology +7

Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase

Wilco Keulen, Nicole Back, Anne‐Eva van der Wijk, +2

Journal of Virology

Lamivudine‐Resistant Human Immunodeficiency Virus Type 1 Variants (184V) Require Multiple Amino Acid Changes to Become Co‐Resistant to Zidovudine In Vivo

Monique Nijhuis, Rob Schuurman, Dorien de Jong, +6

The Journal of Infectious Diseases

Use of recombinant antigens expressed in Escherichia coli K-12 to map B-cell and T-cell epitopes on the immunodominant 65-kilodalton protein of Mycobacterium bovis BCG

J E Thole, W C van Schooten, Wilco Keulen, +5

Infection and Immunity

Recombinant AntigensAdaptive Immune SystemHumoral ResponseImmunologyBacteriology +19