Publication | Open Access

Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

Primary ImmunodeficiencyReverse Transcriptase EnzymeViral ReplicationMedicineViral Polymerase MechanismHuman RetrovirusImmunologyAntiviral ResponseMolecular BiologyResistance Mutation (Virology)Hiv3Tc-resistant Hiv-1 VariantsProcessivity DefectAids Pathogenesis