Concepedia

Christine Bleasdale

CB

Statistics

Publications

23

Citations

501

H-Index

14

Active since

1990

Affiliations

Newcastle University(Current)

Shell (Netherlands)

University of Leicester

AstraZeneca (United Kingdom)

Research Triangle Park Foundation

Christine Bleasdale is an author at Newcastle University specializing in chemistry, biochemistry, and organic chemistry.

Publications per year

1990–2010

23

Publications

23

Novel potent inhibitors of the DNA repair enzyme poly(ADP-ribose)polymerase (PARP).

Griffin Rj, Pemberton Lc, Daniela Rhodes et al. · PubMed · 1995 · 58 citations

, , +14

Resistance-Modifying Agents. 8. Inhibition of <i>O</i><sup>6</sup>-Alkylguanine-DNA Alkyltransferase by <i>O</i><sup>6</sup>-Alkenyl-, <i>O</i><sup>6</sup>-Cycloalkenyl-, and <i>O</i><sup>6</sup>-(2-Oxoalkyl)guanines and Potentiation of Temozolomide Cytotoxicity in Vitro by <i>O</i><sup>6</sup>-(1-Cyclopentenylmethyl)guanine

Roger J. Griffin, Christine E. Arris, Christine Bleasdale et al. · Journal of Medicinal Chemistry · 2000 · 49 citations · Full text

, , +13

The mechanism of decomposition of N-methyl-N-nitrosourea (MNU) in water and a study of its reactions with 2′-deoxyguanosine, 2′-deoxyguanosine 5′-monophosphate and d(GTGCAC)

Bernard T. Golding, Christine Bleasdale, Joseph McGinnis et al. · Tetrahedron · 1997 · 43 citations

, , +5

Mechanisms of Formation of Adducts from Reactions of Glycidaldehyde with 2‘-Deoxyguanosine and/or Guanosine

Bernard T. Golding, Pritpal K. Slaich, Gordon T. Kennedy et al. · Chemical Research in Toxicology · 1996 · 38 citations

, , +5

Reactions of Benzene Oxide with Thiols Including Glutathione

Alistair P. Henderson, Martine L. Barnes, Christine Bleasdale et al. · Chemical Research in Toxicology · 2005 · 29 citations

, , +17

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