Downregulation of TFAM inhibits the tumorigenesis of non-small cell lung cancer by activating ROS-mediated JNK/p38MAPK signaling and reducing cellular bioenergetics

Deyao Xie, Xiaoyi Wu, Linhua Lan, +12

Oncotarget

Cell DeathPathologyCancer BiologyTumor BiologyReceptor Tyrosine Kinase +17

A Novel Mechanism of Cannabidiol in Suppressing Hepatocellular Carcinoma by Inducing GSDME Dependent Pyroptosis

Fugen Shangguan, Hongfei Zhou, Nengfang Ma, +8

Frontiers in Cell and Developmental Biology

Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer

Yongzhang Liu, Linhua Lan, Kate Huang, +11

Oncotarget

S100A16 promotes metastasis and progression of pancreatic cancer through FGF19-mediated AKT and ERK1/2 pathways

Dan Fang, Chengfei Zhang, Ping Xu, +9

Cell Biology and Toxicology

Tumor BiologyPancreatic CancerMedicineCancer Cell BiologyPathology +7

Down-Regulating Overexpressed Human Lon in Cervical Cancer Suppresses Cell Proliferation and Bioenergetics

Xiaobo Nie, Min Li, Bin Lü, +4

PLoS ONE

Tumor BiologyOncologyCervical CancerHuman LonOncogenic Agent +10

Elevated p53 expression levels correlate with tumor progression and poor prognosis in patients exhibiting esophageal squamous cell carcinoma

Kate Huang, Lin Chen, Jiliang Zhang, +5

Oncology Letters

Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction

Linhua Lan, Wei Wei, Ying Zheng, +9

Cancer Letters

Esophageal CancerMitochondrial FunctionMitochondrial DysfunctionMedicineMitochondrial Dynamic +8

N-glycosylation stabilizes MerTK and promotes hepatocellular carcinoma tumor growth

Yongzhang Liu, Linhua Lan, Yujie Li, +11

Redox Biology

Association of p53/p21 expression and cigarette smoking with tumor progression and poor prognosis in non-small cell lung cancer patients

Deyao Xie, Linhua Lan, Kate Huang, +8

Oncology Reports

Dimethyl Fumarate Induces Metabolic Crisie to Suppress Pancreatic Carcinoma

Kaiyuan Chen, Shanshan Wu, Sisi Ye, +8

Frontiers in Pharmacology

Chemoprevention StrategyApoptosisCell DeathMetabolic RemodelingCancer Biology +16