D B Lowrie

A single mycobacterial protein (hsp 65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis.

Célio Lopes Silva, D B Lowrie · PubMed · 1994 · 104 citations · Full text

Class Ii, Tuberculosis Prevention, Immunology +23

Tumor cells transfected with a bacterial heat-shock gene lose tumorigenicity and induce protection against tumors.

Katalin Lukács, D B Lowrie, Richard W. Stokes et al. · The Journal of Experimental Medicine · 1993 · 96 citations · Full text

Immunology, Immunoediting, Pathology +17

Immunostimulatory bacterial DNA sequences activate dendritic cells and promote priming and differentiation of CD8⁺ T cells

Ricardo E. Tascon, Silvia Ragno, D B Lowrie et al. · Immunology · 2000 · 35 citations · Full text

Mycobacterium leprae 65hsp antigen expressed from a retroviral vector in a macrophage cell line is presented to T cells in association with MHC class II in addition to MHC class I

Célio Lopes Silva, Alicia Palacios, M J Colston et al. · Microbial Pathogenesis · 1992 · 27 citations

Immunological Memory, Autoimmune Disease, Mhc Class +11

Incorporation of immunostimulatory motifs in the transcribed region of a plasmid DNA vaccine enhances Th1 immune responses and therapeutic effect against Mycobacterium tuberculosis in mice

Juan Wu, Hui Ma, Qing Qu et al. · Vaccine · 2011 · 24 citations

Vaccination, Pulmonary Tuberculosis, Therapeutic Effect +12