Ryan P. Duren

Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia

Seth P. Boudreaux, Ashley M. Ramirez-Herrick, Ryan P. Duren et al. · Oncogenesis · 2012 · 55 citations · Full text

Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells

Ryan P. Duren, Seth P. Boudreaux, Orla M. Conneely · PLoS ONE · 2016 · 42 citations · Full text

Mixed-phenotype Acute Leukemia, Genetics, Epigenetic Change +22

Drug targeting of NR4A nuclear receptors for treatment of acute myeloid leukemia

Seth P. Boudreaux, Ryan P. Duren, S. Greg Call et al. · Leukemia · 2018 · 31 citations · Full text

Hematological Malignancy, Drug Targeting, Medicine +10

Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors

S. Greg Call, Ryan P. Duren, Anil K. Panigrahi et al. · Scientific Reports · 2020 · 28 citations · Full text

A harmonized meta-knowledgebase of clinical interpretations of cancer genomic variants

Alex H. Wagner, Brian Walsh, Georgia Mayfield et al. · 2018 · 20 citations · Full text

Genetic Epidemiology, Pathology, Somatic Cancer Variants +17