Structural Basis for the Highly Selective Inhibition of MMP-13

Christian K. Engel, Bernard Pirard, Sandra Schimanski, +6

Chemistry & Biology

Medicinal ChemistryMedicineMechanism Of ActionStructural BasisAnti-cancer Agent +2

Discovery of an Orally Active Non-Peptide Fibrinogen Receptor Antagonist Based on the Hydantoin Scaffold

Hans Ulrich Stilz, Wolfgang Guba, Bernd Jablonka, +5

Journal of Medicinal Chemistry

Dog Platelet AggregationPharmacotherapyChemical BiologyThrombosisMedicinal Chemistry +15

Design, synthesis, and structure–activity relationship of a new class of amidinophenylurea-based factor VIIa inhibitors

Otmar Klingler, Hans Matter, Manfred Schudok, +6

Bioorganic & Medicinal Chemistry Letters

Structure–activity RelationshipMedicinal ChemistryBiochemistryMedicineNatural Sciences +7

Structural Requirements for Inhibition of the Neuronal Nitric Oxide Synthase (NOS-I):  3D-QSAR Analysis of 4-Oxo- and 4-Amino-Pteridine-Based Inhibitors

Hans Matter, Peter Kotsonis, Otmar Klingler, +5

Journal of Medicinal Chemistry

Structure-based design of amidinophenylurea-derivatives for factor VIIa inhibition

Otmar Klingler, Hans Matter, Manfred Schudok, +6

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryMedicineRational Drug DesignPharmacology +3

Photochemical Transformations, 75. The Azo/Nitrene Route to <i>cis,cis</i>‐Trialkyltriaziridines, 2^1b) Photolysis of <i>syn</i>‐Azo Azides of Defined Proximity – Attempts for N₃ → N₃X Ring Enlargement

Wolfgang Marterer, Otmar Klingler, Regina Thiergardt, +3

Chemische Berichte

Chemical EngineeringEngineeringPhotoredox ProcessPhotochemistryInorganic Photochemistry +13

Deformation Density of a <i>cis</i>,<i>cis</i>‐Trialkyltriaziridine

Hermann Irngartinger, Dietmar Kallfaß, Horst Prinzbach, +1

Chemische Berichte

Materials ScienceInorganic ChemistryCrystal StructureEngineeringDensity Maxima +12

Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand

Marc Nazaré, Hans Matter, Otmar Klingler, +13

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryMedicineBenzoic Acid ScaffoldNatural Sciences +8

cis,cis - Trialkyl-triaziridines photoelectron spectra - X-ray structural analysis

Rolf Gleiter, Christoph Sigwart, Hermann Irngartinger, +4

Tetrahedron Letters

Inorganic ChemistryEngineeringStructure ElucidationX-ray Structural AnalysisChemistry +2

Moving to CoPACaPAnA: Implementation of a continuous protein A capture process for antibody applications within an end-to-end single-use GMP manufacturing downstream process

Ozan Ötes, Cathrin Bernhardt, Kevin S. Brandt, +6

Biotechnology Reports

EngineeringBiomedical EngineeringProtein PurificationBioanalysisBiochemical Engineering +16