Ashley E. Lepack

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

Hyo Jung Kang, Bhavya Voleti, Tibor Hajszán et al. · Nature Medicine · 2012 · 793 citations · Full text

Synaptic Plasticity, Molecular Neuroscience, Psychiatry +12

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3

Lorna A. Farrelly, Robert E. Thompson, Shuai Zhao et al. · Nature · 2019 · 443 citations

Histone Modifications, Chromatin, Transcriptional Regulation +13

BDNF Release Is Required for the Behavioral Actions of Ketamine

Ashley E. Lepack, Manabu Fuchikami, J. M. Dwyer et al. · The International Journal of Neuropsychopharmacology · 2014 · 363 citations · Full text

GSK-3 Inhibition Potentiates the Synaptogenic and Antidepressant-Like Effects of Subthreshold Doses of Ketamine

Rong-Jian Liu, Manabu Fuchikami, Jason M. Dwyer et al. · Neuropsychopharmacology · 2013 · 253 citations · Full text

Molecular Neuroscience, Psychiatry, Neurophysiology +13

Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking

Ashley E. Lepack, Craig Werner, Andrew F. Stewart et al. · Science · 2020 · 223 citations · Full text