The Human Gonadotropin Releasing Hormone Type I Receptor Is a Functional Intracellular GPCR Expressed on the Nuclear Membrane

Michelle Re, Macarena Pampillo, Martin Savard, +7

PLoS ONE

Molecular BiologyCellular PhysiologyNuclear MembraneMolecular PharmacologyHormone Receptor +14

Induction of Selective Blood-Tumor Barrier Permeability and Macromolecular Transport by a Biostable Kinin B1 Receptor Agonist in a Glioma Rat Model

Jérôme Côté, Veronica Bovenzi, Martin Savard, +9

PLoS ONE

High-grade GliomasGliomaTumor BiologyCerebral Vascular RegulationNeuro-oncology +16

Targeting gastrin-releasing peptide receptors of prostate cancer cells for photodynamic therapy with a phthalocyanine–bombesin conjugate

Céléna Dubuc, Réjean Langlois, François Bénard, +4

Bioorganic & Medicinal Chemistry Letters

Photodynamic TherapyPhototoxicityProstate Cancer CellsPhotosensitizersPharmacology +3

[Lys(DOTA)4]BVD15, a novel and potent neuropeptide Y analog designed for Y1 receptor-targeted breast tumor imaging

Brigitte Guérin, Véronique Dumulon‐Perreault, Marie‐Claude Tremblay, +5

Bioorganic & Medicinal Chemistry Letters

EngineeringMedicineNeuropeptide ReceptorPeptide ScienceBiomedical Engineering +4

Synthesis, characterization, and estrogen receptor binding affinity of flavone-, indole-, and furan-estradiol conjugates

Naseem Ahmed, Céléna Dubuc, Jacques Rousseau, +2

Bioorganic & Medicinal Chemistry Letters

BiochemistryMedicineHormonal ReceptorEstrogen ReceptorEndocrinology +4

Selective tumor blood–brain barrier opening with the kinin B2 receptor agonist [Phe8ψ(CH2NH)Arg9]-BK in a F98 glioma rat model: An MRI study

Jérôme Côté, Martin Savard, Veronica Bovenzi, +6

Neuropeptides

Neuro-oncologyMolecular PharmacologyTumor InnervationBlood–brain BarrierMedicine +6

Novel kinin B1 receptor agonists with improved pharmacological profiles

Jérôme Côté, Martin Savard, Veronica Bovenzi, +6

Peptides

Improved Pharmacological ProfilesFunctional SelectivityMedicinePharmacotherapyPharmacology +2

Antitumor activity of cell‐penetrant kinin B1 receptor antagonists in human triple‐negative breast cancer cells

Céléna Dubuc, Martin Savard, Veronica Bovenzi, +6

Journal of Cellular Physiology

[18F]Fluorinated estradiol derivatives for oestrogen receptor imaging: impact of substituents, formulation and specific activity on the biodistribution in breast tumour-bearing mice

François Bénard, Naseem Ahmed, Jean‐Mathieu Beauregard, +5

European Journal of Nuclear Medicine and Molecular Imaging

EngineeringMedicineRadionuclide TherapyImaging AgentTheranostics +10

[11C] Acetoacetate Utilization by Breast and Prostate Tumors: a PET and Biodistribution Study in Mice

Simon Authier, Sébastien Tremblay, Véronique Dumulon, +5

Molecular Imaging and Biology

UrologyMedicineBreast CancerProstatic DiseaseBiodistribution Study +4