Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Stanley B. Prusiner, Amanda L. Woerman, Daniel A. Mordes, +14

Proceedings of the National Academy of Sciences

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

Joseph R. Klim, Luis A. Williams, Francesco Limone, +13

Nature Neuroscience

Als-implicated Protein Tdp-43Neurodegenerative DiseasesNeuroregenerationMolecular NeuroscienceAmyotrophic Lateral Sclerosis +8

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

Daniel A. Mordes, Gloria G. Glick, Runxiang Zhao, +1

Genes & Development

Molecular RegulationSignal RecognitionMolecular BiologyCell DeathCell Cycle +16

Loss-of-function mutations in the <i>C9ORF72</i> mouse ortholog cause fatal autoimmune disease

Aaron Burberry, Naoki Suzuki, Jinyuan Wang, +14

Science Translational Medicine

GeneticsImmunologyImmune RegulationCell DeathNeuroinflammation +18

Propagation of prions causing synucleinopathies in cultured cells

Amanda L. Woerman, Jan Stöhr, Atsushi Aoyagi, +16

Proceedings of the National Academy of Sciences

The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling

Xin Xu, Sivaraja Vaithiyalingam, Gloria G. Glick, +3

Molecular and Cellular Biology

Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein

Sali M.K. Farhan, Daniel P. Howrigan, Liam Abbott, +32

Nature Neuroscience

Amyotrophic Lateral SclerosisHeat-shock ProteinExome SequencingGeneticsMolecular Biology +6

Function of a Conserved Checkpoint Recruitment Domain in ATRIP Proteins

Heather L. Ball, Mark R. Ehrhardt, Daniel A. Mordes, +3

Molecular and Cellular Biology

Molecular BiologyCell CycleCell RegulationCell SignalingAtr Kinase Activity +14

Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage

Sarah J. Hill, Daniel A. Mordes, Lisa Cameron, +4

Proceedings of the National Academy of Sciences

Dna DamageGeneticsCell DeathMolecular BiologyTranscription-associated Dna Damage +14

Dpb11 activates the Mec1–Ddc2 complex

Daniel A. Mordes, Edward A. Nam, David Cortez

Proceedings of the National Academy of Sciences