Adam S. Sperling

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

Niccolò Bolli, Hervé Avet‐Loiseau, David C. Wedge et al. · Nature Communications · 2014 · 890 citations · Full text

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

Mikołaj Słabicki, Zuzanna Kozicka, Georg Petzold et al. · Nature · 2020 · 389 citations · Full text

Protein Function, Signal Transduction, Cell Regulation +10

Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma

Mehmet Samur, Mariateresa Fulciniti, Anıl Aktaş Samur et al. · Nature Communications · 2021 · 388 citations · Full text

Small-molecule-induced polymerization triggers degradation of BCL6

Mikołaj Słabicki, Hojong Yoon, Jonas Koeppel et al. · Nature · 2020 · 252 citations · Full text

Engineering, Polymer Science, Molecular Biology +4

Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide

Max Jan, Irene Scarfò, Rebecca C. Larson et al. · Science Translational Medicine · 2021 · 243 citations · Full text