Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis

Yi Zeng, Rongfang Qiu, Yang Yang, +14

Cell Reports

LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer

Yang Yang, Wei Huang, Rongfang Qiu, +10

Journal of Molecular Cell Biology

Histone ModificationsEpigenetic ChangeMolecular BiologyCancer BiologyHistone Demethylation +21

PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5–WDR77/CRL4B complex to promote tumorigenesis

Ruiqiong Liu, Jie Gao, Yang Yang, +13

Nucleic Acids Research

Snail/PRMT5/NuRD complex contributes to DNA hypermethylation in cervical cancer by TET1 inhibition

Jie Gao, Ruiqiong Liu, Dandan Feng, +11

Cell Death and Differentiation

SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis

Shuai Leng, Wei Huang, Yang Chen, +9

Cell Death and Differentiation

Tumor BiologyPancreatic CancerCell RegulationMedicineSirt1/crl4b Complex +9

The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex

Yu Zheng, Yi Zeng, Rongfang Qiu, +8

Theranostics

GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer

Wenqian Yu, Wei Huang, Yang Yang, +12

Cell Death and Disease

RIP1 maintains DNA integrity and cell proliferation by regulating PGC-1α-mediated mitochondrial oxidative phosphorylation and glycolysis

Wenshu Chen, Q Wang, Liping Bai, +7

Cell Death and Differentiation

Mitochondrial FunctionMitochondrial DynamicCell ProliferationDna IntegritySystems Biology +3

MicroRNA-455-3p mediates GATA3 tumor suppression in mammary epithelial cells by inhibiting TGF-β signaling

Yi Zeng, Tianyang Gao, Wei Huang, +10

Journal of Biological Chemistry

BRMS1 coordinates with LSD1 and suppresses breast cancer cell metastasis.

Rongfang Qiu, Hang Shi, Shuang Wang, +10

PubMed