Kenneth J. Stauffer

Design and Synthesis of a Series of Potent and Orally Bioavailable Noncovalent Thrombin Inhibitors That Utilize Nonbasic Groups in the P1 Position

Thomas J. Tucker, Stephen F. Brady, William C. Lumma et al. · Journal of Medicinal Chemistry · 1998 · 105 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Pharmacotherapy +18

Discovery and Evaluation of Potent P₁ Aryl Heterocycle-Based Thrombin Inhibitors

Mary Beth Young, James C. Barrow, Kristen L. Glass et al. · Journal of Medicinal Chemistry · 2004 · 93 citations · Full text

Molecular Docking, Combinatorial Chemistry, Medicinal Chemistry +15

Discovery and Development of the Novel Potent Orally Active Thrombin Inhibitor <i>N</i>-(9-Hydroxy-9-fluorenecarboxy)prolyl <i>trans</i>-4-Aminocyclohexylmethyl Amide (L-372,460):  Coapplication of Structure-Based Design and Rapid Multiple Analogue Synthesis on Solid Support

Stephen F. Brady, Kenneth J. Stauffer, William C. Lumma et al. · Journal of Medicinal Chemistry · 1998 · 78 citations · Full text

Combinatorial Chemistry, Polystyrene Support, Chemical Biology +16

9-Hydroxyazafluorenes and Their Use in Thrombin Inhibitors

Kenneth J. Stauffer, Peter Williams, Harold G. Selnick et al. · Journal of Medicinal Chemistry · 2005 · 36 citations · Full text

Amide and α-keto carbonyl inhibitors of thrombin based on arginine and lysine: Synthesis, stability and biological characterization

Stephen F. Brady, John T. Sisko, Kenneth J. Stauffer et al. · Bioorganic & Medicinal Chemistry · 1995 · 33 citations

Medicinal Chemistry, Pharmaceutical Science, Pharmaceutical Chemistry +11