Concepedia

Michael P. Hughes

MP

Statistics

Publications

16

Citations

1.7K

H-Index

13

Active since

2013

Affiliations

Howard Hughes Medical Institute(Current)

University of California, Los Angeles

St. Jude Children's Research Hospital

UCLA Health

Tsinghua University

Michael P. Hughes is an author at Howard Hughes Medical Institute specializing in life sciences, structural biology, and amyloid fibrils.

ORCID

Publications per year

2013–2024

16

Publications

16

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

Michael P. Hughes, M.R. Sawaya, David R. Boyer et al. · Science · 2018 · 481 citations · Full text

, , +17

Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation

E.L. Guenther, Qin Cao, Hamilton Trinh et al. · Nature Structural & Molecular Biology · 2018 · 270 citations

, , +13

TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle

Thomas O. Vogler, Joshua Wheeler, Éric Nguyen et al. · Nature · 2018 · 230 citations · Full text

, , +8

The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure

David R. Boyer, Binsen Li, Chuanqi Sun et al. · Proceedings of the National Academy of Sciences · 2020 · 180 citations · Full text

, , +17

Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta

Lin Jiang, Cong Liu, D.J. Leibly et al. · eLife · 2013 · 123 citations · Full text

, , +17

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