Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy

Ruqi Tang, Yiran Wei, Yanmei Li, +18

Gut

Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease

Ke Hou, Jing Zhao, Hui Wang, +11

Nature Communications

Alterations of gut microbiome in autoimmune hepatitis

Yiran Wei, Yanmei Li, Yan Li, +18

Gut

Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation

E.L. Guenther, Qin Cao, Hamilton Trinh, +7

Nature Structural & Molecular Biology

X-ray CrystallographyCrystal StructureProtein AssemblyBiochemistryProtein Folding +10

Cryo-EM structures of four polymorphic TDP-43 amyloid cores

Qin Cao, David R. Boyer, M.R. Sawaya, +2

Nature Structural & Molecular Biology

Crystal StructureBiophysicsProtein FoldingCryo-em StructuresProtein X-ray Crystallography +5

Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis

Weihua Chen, Yiran Wei, Aizhen Xiong, +18

Clinical Reviews in Allergy & Immunology

DysbiosisBiliary TractBiliary CancerGut MicrobiologyGastroenterology +11

Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43

Yi Xiao Jiang, Qin Cao, M.R. Sawaya, +8

Nature

Neurodegenerative DiseasesAlzheimer's DiseaseProtein FoldingAmyloid FibrilsMolecular Biology +6

Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils

Qin Cao, David R. Boyer, M.R. Sawaya, +2

Nature Structural & Molecular Biology

Protein FunctionBiochemistryProtein AssemblyProtein FoldingNatural Sciences +6

CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid

Jiahui Lu, Qin Cao, Michael P. Hughes, +4

Nature Communications

Measurement of Ultra-High-Energy Diffuse Gamma-Ray Emission of the Galactic Plane from 10 TeV to 1 PeV with LHAASO-KM2A

Z. Cao, F. Aharonian, Q. An, +140

Physical Review Letters