Plinio Perrone

Application of the Phosphoramidate ProTide Approach to 4‘-Azidouridine Confers Sub-micromolar Potency versus Hepatitis C Virus on an Inactive Nucleoside

Plinio Perrone, G Luoni, Mary Rose Kelleher et al. · Journal of Medicinal Chemistry · 2007 · 94 citations

Cell Culture, Antiviral Drug, Hcv Replication +16

First Example of Phosphoramidate Approach Applied to a 4‘-Substituted Purine Nucleoside (4‘-Azidoadenosine):  Conversion of an Inactive Nucleoside to a Submicromolar Compound versus Hepatitis C Virus

Plinio Perrone, Felice Daverio, Rocco Valente et al. · Journal of Medicinal Chemistry · 2007 · 71 citations

The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4′-azidocytidine (R1479)

Christopher McGuigan, Mary Rose Kelleher, Plinio Perrone et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 60 citations

Potent Anti-hcv Compound, Medicinal Chemistry, Natural Sciences +10

The phosphoramidate ProTide approach greatly enhances the activity of β-2′-C-methylguanosine against hepatitis C virus

Christopher McGuigan, Plinio Perrone, Karolina Madela et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 42 citations

Biochemistry, Hepatitis C Virus, Viral Hepatitis +10

Facile one-pot preparation of 2-arylpropionic and arylacetic acids from cyanohydrins by treatment with aqueous HI

Andrea Aramini, Manolo R. Sablone, Gianluca Bianchini et al. · Tetrahedron · 2009 · 27 citations

Natural Product Synthesis, Engineering, One-pot Preparation +8