Virna Schuck

Translating slow-binding inhibition kinetics into cellular and in vivo effects

Grant K. Walkup, Zhiping You, Philip L. Ross et al. · Nature Chemical Biology · 2015 · 148 citations · Full text

Signal Transduction, Biochemistry, Cell Signaling +13

Comparative <i>In Vitro</i> and <i>In Vivo</i> Efficacies of Human Simulated Doses of Ceftazidime and Ceftazidime-Avibactam against Pseudomonas aeruginosa

Jared L. Crandon, Virna Schuck, Mary Anné Banevicius et al. · Antimicrobial Agents and Chemotherapy · 2012 · 115 citations · Full text

Pharmacodynamics of Ceftazidime and Avibactam in Neutropenic Mice with Thigh or Lung Infection

Johanna Berkhout, Maria J. Melchers, Anita C. van Mil et al. · Antimicrobial Agents and Chemotherapy · 2015 · 101 citations · Full text

Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

Gregory S. Basarab, Günther Kern, John McNulty et al. · Scientific Reports · 2015 · 100 citations · Full text

A Phase I Study of IDH305 in Patients with Advanced Malignancies Including Relapsed/Refractory AML and MDS That Harbor IDH1R132 Mutations

Courtney D. DiNardo, Aaron D. Schimmer, Karen Yee et al. · Blood · 2016 · 59 citations