Helge Siemens

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

Helge Siemens, René Jackstadt, Sabine Hünten et al. · Cell Cycle · 2011 · 598 citations · Full text

Epithelial-mesenchymal Transitions, Cancer Biology, Cellular Physiology +20

SNAIL and miR‐34a feed‐forward regulation of ZNF281/ZBP99 promotes epithelial–mesenchymal transition

Stefanie Hahn, René Jackstadt, Helge Siemens et al. · The EMBO Journal · 2013 · 167 citations · Full text

Detection of <i>miR-34a</i> Promoter Methylation in Combination with Elevated Expression of c-Met and β-Catenin Predicts Distant Metastasis of Colon Cancer

Helge Siemens, Jens Neumann, René Jackstadt et al. · Clinical Cancer Research · 2012 · 140 citations

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness

Helge Siemens, René Jackstadt, Markus Kaller et al. · Oncotarget · 2013 · 134 citations · Full text

p53-Induced miR-15a/16-1 and AP4 Form a Double-Negative Feedback Loop to Regulate Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

Lei Shi, René Jackstadt, Helge Siemens et al. · Cancer Research · 2013 · 125 citations