Michael A. Lynch

Synthesis, biological activity and comparative analysis of DNA binding affinities and human DNA topoisomerase I inhibitory activities of novel 12-alkoxy-benzo[c]phenanthridinium salts

Michael A. Lynch, Olivier Duval, Alyona Sukhanova et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 75 citations

Biological Activity, Biochemistry, Natural Sciences +8

1,2-Dinitrosobenzene in argon matrices at 14 K

Ian R. Dunkin, Michael A. Lynch, A. J. Boulton et al. · Journal of the Chemical Society Chemical Communications · 1991 · 39 citations

Chemical Engineering, Engineering, Physics +15

Lead Optimization toward Proof-of-Concept Tools for Huntington’s Disease within a 4-(1<i>H</i>-Pyrazol-4-yl)pyrimidine Class of Pan-JNK Inhibitors

John Wityak, Kevin F. McGee, Michael P. Conlon et al. · Journal of Medicinal Chemistry · 2015 · 38 citations

Molecular Biology, Pharmacotherapy, Proof-of-concept Tools +22

A facile N-arylation of acetanilides with arynes

James C. Haber, Michael A. Lynch, Stacey L. Spring et al. · Tetrahedron Letters · 2011 · 28 citations

Organic Chemistry, Facile N-arylation, Synthetic Chemistry +1

Responsiveness to Transforming Growth Factor-β (TGF-β)-Mediated Growth Inhibition Is a Function of Membrane-Bound TGF-β Type II Receptor in Human Breast Cancer Cells

Michael A. Lynch, Trevor A. Petrel, Huijuan Song et al. · Gene Expression · 2001 · 25 citations · Full text

Breast Oncology, Tgf-beta Receptor Complex, Cell Growth +16