Hubert Borell

Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite

Ulrike Glaenzel, Yi Jin, Regine Hansen et al. · Drug Metabolism and Disposition · 2020 · 70 citations · Full text

Medicine, Clinical Pharmacokinetics, Pharmacology +14

CYP4F Enzymes Are Responsible for the Elimination of Fingolimod (FTY720), a Novel Treatment of Relapsing Multiple Sclerosis

Yi Jin, Markus Zollinger, Hubert Borell et al. · Drug Metabolism and Disposition · 2010 · 67 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Metabolism and Disposition of Siponimod, a Novel Selective S1P1/S1P5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

Ulrike Glaenzel, Yi Jin, Robert Nufer et al. · Drug Metabolism and Disposition · 2018 · 55 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data

Alexander D. James, Hilmar Schiller, Cyrille Marvalin et al. · Pharmacology Research & Perspectives · 2020 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

In vitro studies and in silico predictions of fluconazole and CYP2C9 genetic polymorphism impact on siponimod metabolism and pharmacokinetics

Yi Jin, Hubert Borell, Anne Gardin et al. · European Journal of Clinical Pharmacology · 2017 · 26 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17