Birgitta E. Michels

3D model for <scp>CAR</scp> ‐mediated cytotoxicity using patient‐derived colorectal cancer organoids

Theresa Schnalzger, Marnix HP de Groot, Congcong Zhang et al. · The EMBO Journal · 2019 · 323 citations · Full text

Gastrointestinal Oncology, Medicine, Pharmacology +7

Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids

Birgitta E. Michels, Mohammed H. Mosa, Barbara Streibl et al. · Cell stem cell · 2020 · 211 citations · Full text

Human Colon Organoids, Pathology, Colorectal Cancer +9

Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency

Anna S. Lehle, Henner F. Farin, Benjamin Marquardt et al. · Gastroenterology · 2018 · 122 citations

Inflammation, Autoimmune Disease, Intestinal Inflammation +12

A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer

Mohammed H. Mosa, Birgitta E. Michels, Constantin Menche et al. · Cancer Research · 2020 · 119 citations · Full text

Pathology, Wnt-induced Phenotypic Switch, Cancer Biology +19

AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer

Júlia Varga, Adele M. Nicolas, Valentina Petrocelli et al. · The Journal of Experimental Medicine · 2020 · 101 citations · Full text

Medicine, Mesenchymal Colorectal Cancer, Pathology +13