Peripheral T cell expansion predicts tumour infiltration and clinical response

Thomas D. Wu, Shravan Madireddi, Patrícia E. de Almeida, +26

Nature

Cancer ImmunosurveillanceMedicineT-regulatory CellImmunologyPathology +6

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

Vladimir Ramirez-Carrozzi, Arivazhagan Sambandam, Elizabeth Luis, +19

Nature Immunology

InflammationCytokineInnate Immune FunctionInnate Immune SystemImmunology +9

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury

Kim Newton, Debra L. Dugger, Allie Maltzman, +19

Cell Death and Differentiation

Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice

Janet Lau, Jeanne Cheung, Armando Navarro, +17

Nature Communications

Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis

Daryle J. DePianto, Sanjay Chandriani, Alexander R. Abbas, +14

Thorax

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

Ingrid E. Wertz, Kim Newton, Dhaya Seshasayee, +31

Nature

InflammationAnti-inflammatoryAutoimmune DiseaseMedicineImmunology +5

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

Rajkumar Noubade, Kit Hong Wong, Naruhisa Ota, +14

Nature

InflammationHost ResponseAllergyAutoimmune DiseaseHost Defence +8

Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration

Luz D. Orozco, Hsu-Hsin Chen, Christian L. Cox, +16

Cell Reports

Ocular DiseaseGeneticsAge-related Macular DegenerationGene CharacterizationGene Expression Profiling +14

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells

Marcel Batten, Nandhini Ramamoorthi, Noelyn M. Kljavin, +11

The Journal of Experimental Medicine

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmune RegulationImmunology +20

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer

WeiYu Lin, Daqi Xu, Cary D. Austin, +45

Frontiers in Immunology