Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs

Graham Lappin, W. Kuhnz, R. Jochemsen, +6

Clinical Pharmacology & Therapeutics

Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys

Andrew J. S. Jones, Damon I. Papac, Edward Chin, +5

Glycobiology

Human Immunoglobulin GImmunocytochemical TechniqueGlycobiologyImmunologyCarbohydrate-protein Interaction +17

Determination of Midazolam and Its α-Hydroxy Metabolite in Human Plasma and Urine by High-Performance Liquid Chromatography

Huy Riêm Ha, Katharina Rentsch, J Kneer, +1

Therapeutic Drug Monitoring

(E)-2(R)-[1(S)-(Hydroxycarbamoyl)-4-phenyl-3-butenyl]-2′-isobutyl-2′-(methanesulfonyl)-4-methylvalerohydrazide (Ro 32-7315), a Selective and Orally Active Inhibitor of Tumor Necrosis Factor-α Convertase

Gregory Beck, Gillian A. Bottomley, D. Bradshaw, +19

Journal of Pharmacology and Experimental Therapeutics

Pharmacokinetics of intravenous cefetamet (Ro 15-8074) and oral cefetamet pivoxil (Ro 15-8075) in young and elderly subjects

Robert A. Blouin, J Kneer, K. Stoeckel

Antimicrobial Agents and Chemotherapy

Drug SafetyNutritionPlasma Half-lifeAdvanced AgeHealthy Subjects +11

Influence of antacid and ranitidine on the pharmacokinetics of oral cefetamet pivoxil

Robert A. Blouin, J Kneer, R. J. AMBROS, +1

Antimicrobial Agents and Chemotherapy

Drug SafetyMaalox 70Pharmacological StudyMedicineRanitidine Treatment +7

The intravitreal penetration of ceftriaxone in man following systemic administration.

Mordechai Sharir, Giora Triester, J Kneer, +1

PubMed

Antimicrobial StewardshipAntibioticsMedicineCeftriaxone ConcentrationsVitreal Surgery +7

Effects of timing of food and fluid volume on cefetamet pivoxil absorption in healthy normal volunteers

Y.K. Tam, J Kneer, U. C. Dubach, +1

Antimicrobial Agents and Chemotherapy

NutritionFluid VolumeDietary ExposurePharmacotherapyFood Intolerance +17

Pharmacokinetics of cefetamet pivoxil (Ro 15-8075) with ascending oral doses in normal healthy volunteers

Y.K. Tam, J Kneer, U. C. Dubach, +1

Antimicrobial Agents and Chemotherapy

Drug SafetyCefetamet AdsorptionPharmacological StudyMedicineAbsorption Characteristics +11

Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with renal insufficiency

J Kneer, Y K Tam, Robert A. Blouin, +5

Antimicrobial Agents and Chemotherapy