John S. Bridgeman

The Optimal Antigen Response of Chimeric Antigen Receptors Harboring the CD3ζ Transmembrane Domain Is Dependent upon Incorporation of the Receptor into the Endogenous TCR/CD3 Complex

John S. Bridgeman, Robert E. Hawkins, Steve Bagley et al. · The Journal of Immunology · 2010 · 266 citations

Life Sciences, Immunology, Molecular Biology +17

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

Sophie V. Pageon, Thibault Tabarin, Yui Yamamoto et al. · Proceedings of the National Academy of Sciences · 2016 · 243 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8+ T Cells

Kristin Ladell, Masao Hashimoto, María Candela Iglesias et al. · Immunity · 2013 · 149 citations · Full text

Life Sciences, Immunology, Infectious Diseases +15

T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells

Maw Pin Tan, Andrew B. Gerry, Jared Brewer et al. · Clinical & Experimental Immunology · 2014 · 137 citations · Full text

Life Sciences, Immunology, Oncology +17

CD3ζ-based chimeric antigen receptors mediate T cell activation via<i>cis</i>- and<i>trans</i>-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy

John S. Bridgeman, Kristin Ladell, Victoria Sheard et al. · Clinical & Experimental Immunology · 2013 · 87 citations · Full text

Life Sciences, Immunology, Oncology +17