Timothy A. Simeone

Ketone bodies are protective against oxidative stress in neocortical neurons

Do Young ‍Kim, Laurie Davis, Patrick G. Sullivan et al. · Journal of Neurochemistry · 2007 · 203 citations

Ketone bodies mediate antiseizure effects through mitochondrial permeability transition

Do Young ‍Kim, Kristina A. Simeone, Timothy A. Simeone et al. · Annals of Neurology · 2015 · 181 citations · Full text

Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy

Timothy A. Simeone, Stephanie A. Matthews, Kaeli Samson et al. · Experimental Neurology · 2016 · 91 citations

Molecular Neuroscience, Brain Ppargamma2, Neurophysiology +9

Mechanisms of seizure-induced ‘transcriptional channelopathy’ of hyperpolarization-activated cyclic nucleotide gated (HCN) channels

Cristina Richichi, Amy L. Brewster, Roland A. Bender et al. · Neurobiology of Disease · 2007 · 88 citations · Full text

Channelopathies, Molecular Neuroscience, Hyperpolarization (Biology) +10

Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in<i>Kcna1</i>-null Mice

Harrison M. Roundtree, Timothy A. Simeone, Chaz Johnson et al. · SLEEP · 2016 · 83 citations · Full text

Sleep Disorders, Neurotransmitter, Severe Seizures +20