Ketone bodies mediate antiseizure effects through mitochondrial permeability transition

Do Young ‍Kim, Kristina A. Simeone, Timothy A. Simeone, +6

Annals of Neurology

NRSF-dependent epigenetic mechanisms contribute to programming of stress-sensitive neurons by neonatal experience, promoting resilience

Akanksha Singh-Taylor, Jenny Molet, Shan Jiang, +8

Molecular Psychiatry

Developmental Cognitive NeuroscienceNrsf BindingGeneticsEpigenetic ChangeStructural Plasticity +18

Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy

Timothy A. Simeone, Stephanie A. Matthews, Kaeli Samson, +1

Experimental Neurology

Molecular NeuroscienceBrain Ppargamma2NeurophysiologyMedicineNeuropharmacology +7

Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in<i>Kcna1</i>-null Mice

Harrison M. Roundtree, Timothy A. Simeone, Chaz Johnson, +3

SLEEP

Sleep DisordersNeurotransmitterSevere SeizuresNeurotransmissionSynaptic Signaling +18

Hypothalamic hamartoma: Neuropathology and epileptogenesis

John Kerrigan, Angela Parsons, Candy Tsang, +3

Epilepsia

Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices

Timothy A. Simeone, Kristina A. Simeone, Kaeli Samson, +2

Neurobiology of Disease

NeurodynamicsHyperpolarization (Biology)NeurophysiologySynaptic TransmissionPhysiology +10

Ketogenic diet treatment increases longevity in <i>Kcna1</i>‐null mice, a model of sudden unexpected death in epilepsy

Kristina A. Simeone, Stephanie A. Matthews, Jong M. Rho, +1

Epilepsia

Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures

Kristina A. Simeone, Stephanie A. Matthews, Kaeli Samson, +1

Experimental Neurology

NeuropsychologyMitochondrial FunctionNeurophysiologyGenetic ModelGenetics +9

Programming of Stress-Sensitive Neurons and Circuits by Early-Life Experiences

Jessica L. Bolton, Annabel K. Short, Kristina A. Simeone, +2

Frontiers in Behavioral Neuroscience

Developmental Cognitive NeuroscienceBrain DevelopmentNeural RecodingSocial SciencesNeurodynamics +16

Respiratory dysfunction progresses with age in <i>Kcna1</i>‐null mice, a model of sudden unexpected death in epilepsy

Kristina A. Simeone, Jodi Hallgren, Charles S. Bockman, +9

Epilepsia