Susceptibility to leprosy is associated with PARK2 and PACRG

Marcelo Távora Mira, Alexandre Alcaïs, Nguyen Van Thuc, +20

Nature

LeprosyAutoimmune DiseaseDisease MechanismPathogenesisImmunology +4

Distinct Profiles of Human B Cell Effector Cytokines: A Role in Immune Regulation?

Martin Duddy, Andrea Alter, Amit Bar‐Or

The Journal of Immunology

Determinants of Human B Cell Migration Across Brain Endothelial Cells

Andrea Alter, Martin Duddy, Sherry Hebert, +8

The Journal of Immunology

Adaptive Immune SystemImmunologyImmune RegulationBlood CellImmunologic Mechanism +19

Stepwise replication identifies a low-producing lymphotoxin-α allele as a major risk factor for early-onset leprosy

Alexandre Alcaïs, Andrea Alter, Guillemette Antoni, +13

Nature Genetics

Early-onset LeprosyAutoimmune DiseaseImmunodeficienciesPathogenesisImmunology +6

An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults

Jamila El Baghdadi, Marianna Orlova, Andrea Alter, +8

The Journal of Experimental Medicine

Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility

Andrea Alter, Louis de Léséleuc, Nguyen Van Thuc, +9

Human Genetics

Disease SusceptibilityLeprosy SusceptibilityEngineeringAutoimmune DiseaseGenetic Disorder +10

Human Leukocyte Antigen Class I Region Single-Nucleotide Polymorphisms are Associated with Leprosy Susceptibility in Vietnam and India

Andrea Alter, Nguyễn Thu Hương, Meenakshi Singh, +11

The Journal of Infectious Diseases

HistocompatibilityHlaHla ComplexImmunodeficienciesGenetics +19

Linkage disequilibrium pattern and age-at-diagnosis are critical for replicating genetic associations across ethnic groups in leprosy

Andrea Alter, Vinicius M. Fava, Nguyễn Thu Hương, +10

Human Genetics

Genetic AssociationsGenetic AnalysisLinkage Disequilibrium PatternLinkage DisequilibriumGenotype-phenotype Association +10

CUBN and NEBL common variants in the chromosome 10p13 linkage region are associated with multibacillary leprosy in Vietnam

Audrey V. Grant, Aurélie Cobat, Nguyen Van Thuc, +9

Human Genetics

Chromosome 10P13Allelic VariantNebl Common VariantsGenetic DisorderGenetics +7

Genomewide Linkage Analysis of the Granulomatous Mitsuda Reaction Implicates Chromosomal Regions 2q35 and 17q21

Brigitte Ranque, Andrea Alter, Marcelo Távora Mira, +8

The Journal of Infectious Diseases