PKM2, a Central Point of Regulation in Cancer Metabolism

Nicholas Wong, Jason De Melo, Damu Tang

International Journal of Cell Biology

Metabolic RemodelingCancer BiologyPkm2 DrivesTumor BiologyPkm2 Activity +16

The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma

Parvez Vora, Chitra Venugopal, Sabra K. Salim, +25

Cell stem cell

Neuro-oncologyRational DevelopmentImmunologyImmune Checkpoint InhibitorImmunotherapeutics +4

Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread

Elisa Giannoni, Maria Letizia Taddei, Andrea Morandi, +8

Oncotarget

Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study

Douglas Fink, Helen Callaby, Akish Luintel, +298

The Lancet Infectious Diseases

Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer

Judy Yan, Diane Ojo, Anil Kapoor, +12

Cancer Research

Metastatic ProgressionOncologyPerineural InvasionMedicineCntn1 Expression +10

Granulin-Epithelin Precursor Is an Oncofetal Protein Defining Hepatic Cancer Stem Cells

Phyllis Fung Yi Cheung, Christine Kei Chin Cheng, Nicholas Wong, +4

PLoS ONE

Changes in PKM2 Associate with Prostate Cancer Progression

Nicholas Wong, Judy Yan, Diane Ojo, +3

Cancer Investigation

Pyruvate Kinase M2UrologyHigh Pkm2Perineural InvasionAerobic Glycolysis +12

Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer

Judy Yan, Nicholas Wong, Claudia Lin-Kar Hung, +2

PLoS ONE

Tumor BiologyMedicineCell InteractionPten ExpressionCell-matrix Interaction +9

Granulin–Epithelin Precursor Renders Hepatocellular Carcinoma Cells Resistant to Natural Killer Cytotoxicity

Phyllis F. Cheung, Chi Wai Yip, Nicholas Wong, +7

Cancer Immunology Research

ApoptosisImmunologyImmune RegulationCell DeathPathology +16

BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation

Fengxiang Wei, Diane Ojo, Xuelei Lin, +6

Oncogene

Signal TransductionCell RegulationAtm ActivationMedicineCell Biology +2