Xingsen Wu

Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer

Xingsen Wu, Xiang Li, Zhihong Li et al. · Journal of Medicinal Chemistry · 2018 · 47 citations

Discovery of quinone-directed antitumor agents selectively bioactivated by NQO1 over CPR with improved safety profile

Jinlei Bian, Xiang Li, Nan Wang et al. · European Journal of Medicinal Chemistry · 2017 · 42 citations · Full text

Medicinal Chemistry, Quinone-directed Antitumor Agents, Polymer-drug Conjugate +12

Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors

Yonghua Lei, Tianhan Hu, Xingsen Wu et al. · ACS Medicinal Chemistry Letters · 2015 · 28 citations · Full text

2-Substituted 3,7,8-trimethylnaphtho[1,2- b ]furan-4,5-diones as specific L-shaped NQO1-mediated redox modulators for the treatment of non-small cell lung cancer

Xiaojin Zhang, Jinlei Bian, Xiang Li et al. · European Journal of Medicinal Chemistry · 2017 · 27 citations

Medicinal Chemistry, Medicine, Drug Discovery +6

A Carbon‐Carbon Bond Cleavage‐Based Prodrug Activation Strategy Applied to β‐Lapachone for Cancer‐Specific Targeting

Qijie Gong, Xiang Li, Tian Li et al. · Angewandte Chemie International Edition · 2022 · 23 citations

Nanotherapeutics, Chemoprevention Strategy, Futile Redox Cycling +17