Yonghua Lei

2-Substituted 3-methylnaphtho[1,2-b]furan-4,5-diones as novel L-shaped ortho-quinone substrates for NAD(P)H:quinone oxidoreductase (NQO1)

Jinlei Bian, Bang Deng, Lili Xu et al. · European Journal of Medicinal Chemistry · 2014 · 51 citations

Quinone Oxidoreductase, Bioorganic Chemistry, Heterocyclic +7

Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors

Yonghua Lei, Tianhan Hu, Xingsen Wu et al. · ACS Medicinal Chemistry Letters · 2015 · 28 citations · Full text

Curcumin regulates EZH2/Wnt/β‐Catenin pathway in the mandible and femur of ovariectomized osteoporosis rats

Qi Jiang, Yonghua Lei, Dewi Chrystal Krishnadath et al. · The Kaohsiung Journal of Medical Sciences · 2021 · 25 citations · Full text

Ezh2/wnt/β‐catenin Pathway, Pathology, Orthopaedic Surgery +16

Discovery of Clinical Candidate (5-(3-(4-Chlorophenoxy)prop-1-yn-1-yl)-3-hydroxypicolinoyl)glycine, an Orally Bioavailable Prolyl Hydroxylase Inhibitor for the Treatment of Anemia

Xiaojin Zhang, Yonghua Lei, Tianhan Hu et al. · Journal of Medicinal Chemistry · 2020 · 24 citations · Full text

Novel 5-carboxy-8-HQ based histone demethylase JMJD2A inhibitors: Introduction of an additional carboxyl group at the C-2 position of quinoline

Taotao Feng, Dong‐Dong Li, Hai Wang et al. · European Journal of Medicinal Chemistry · 2015 · 20 citations · Full text

Medicinal Chemistry, Additional Carboxyl Group, Novel 5-Carboxy-8-hq +12