Hans Peter Märki

A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro

Elke Burgermeister, Astride Schnoebelen, Angele Flament et al. · Molecular Endocrinology · 2005 · 156 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes

Agnès Bénardeau, Jörg Benz, Alfred Binggeli et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 105 citations · Full text

Medicine, Endocrinology, Pharmacology +13

Substituted piperidines - highly potent renin inhibitors due to induced fit adaptation of the active site

Eric Vieira, Alfred Binggeli, Volker Breu et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 95 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Identification of the active‐site serine in human pancreatic lipase by chemical modification with tetrahydrolipstatin

Qiao-Qian Lüthi-Peng, Hans Peter Märki, Paul Hadváry · FEBS Letters · 1992 · 89 citations · Full text

Life Sciences, Biochemistry, Enzymology +13

Structure-based design of indole propionic acids as novel PPARα/γ co-agonists

Bernd Kuhn, Hans Hilpert, Jörg Benz et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12