Ann Boriack-Sjodin

Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss

Andrew Fedoriw, Satyajit Rajapurkar, Shane W. O’Brien et al. · Cancer Cell · 2019 · 347 citations · Full text

Medicine, Oncology, Pharmacology +7

Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing

Sarah V. Gerhart, Wendy A. Kellner, Christine Thompson et al. · Scientific Reports · 2018 · 208 citations · Full text

Life Sciences, Molecular Biology, Oncology +13

Enhanced Potency of Human Sonic Hedgehog by Hydrophobic Modification

Frederick R. Taylor, Dingyi Wen, Ellen A. Garber et al. · Biochemistry · 2001 · 167 citations

Life Sciences, Biochemistry, Molecular Biology +13

Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma

Allison E. Drew, Oscar Moradei, Suzanne L. Jacques et al. · Scientific Reports · 2017 · 136 citations · Full text

Medicine, Oncology, Pharmacology +14

Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes

Michael Karpusas, Teresa G. Cachero, Fang Qian et al. · Journal of Molecular Biology · 2002 · 134 citations

Life Sciences, Immunology, Molecular Biology +14