Penny A. Jeggo

ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation

Tom Stiff, Mark O’Driscoll, Nicole Rief et al. · Cancer Research · 2004 · 988 citations

Checkpoint Response, Dna Damage, Dna-pk Function Redundantly +19

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

T Blunt, Nicholas Finnie, Guillermo E. Taccioli et al. · Cell · 1995 · 864 citations · Full text

Murine Scid Mutation, Genome Instability, J Recombination +12

A Pathway of Double-Strand Break Rejoining Dependent upon ATM, Artemis, and Proteins Locating to γ-H2AX Foci

Enriqueta Riballo, Martin Kühne, Nicole Rief et al. · Molecular Cell · 2004 · 826 citations · Full text

Genome Instability, Transcriptional Regulation, Protein Function +8

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

Aaron A. Goodarzi, Angela T. Noon, Dorothee Deckbar et al. · Molecular Cell · 2008 · 822 citations · Full text

Chromatin, Genome Instability, Dna Damage +11

A splicing mutation affecting expression of ataxia–telangiectasia and Rad3–related protein (ATR) results in Seckel syndrome

Mark O’Driscoll, Víctor L. Ruiz‐Pérez, C. Geoffrey Woods et al. · Nature Genetics · 2003 · 774 citations

Rare Diseases, Genetic Disorder, Medicine +8